Drug–excipient interactions in ketoprofen: A vibrational spectroscopy study
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چکیده
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Drug-excipient interactions in ketoprofen: a vibrational spectroscopy study.
Ketoprofen (3-benzoyl-alpha-methylbenzeneacetic acid) is a widely used nonsteroidal anti-inflammatory drug (NSAID), always administered in the form of drug-excipient physical mixtures (PMs). The occurrence of possible interactions between ketoprofen and two commonly used excipients-lactose (LAC) and polyvinylpyrrolidone (PVP)-was evaluated, through vibrational spectroscopy techniques [both Rama...
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ژورنال
عنوان ژورنال: Biopolymers
سال: 2006
ISSN: 0006-3525,1097-0282
DOI: 10.1002/bip.20517